The guitar can electrocute and burn enemies for continual damage. Clementine is also capable of playing solos, which act as spells. These can do anything from summon cars and beasts to melting enemy faces.
As the game progresses, the player can unlock more abilities and even combo moves with The Separator. More combos can be unlocked through the story and by purchase in the Motor Forge, where Eddie can also buy various guitar strings that enhance different parts of Clementine's power, each with its own complimentary paint job.
Clementine's magic power cannot be used constantly for long periods of time. If it is overheated, the guitar will burn red hot. The player will have to wait for a short cooldown period before being able to use its magic again.
In the modern era, Eddie is shown tuning Clementine before Cabbage Boy's concert. The lead guitarist approaches Eddie and insincerely apologizes for smashing it the night before, laughing before realizing Eddie had fixed it "like new", and taking it to use on stage, promsing not to smash it "so much this time". During the show the guitarist climbs the set and nearly falls, dropping Clementine forcing Eddie to grab it before saving the ungrateful musician.
When first retrieved in the mission "Welcome to the Age of Metal", the player is immediately able to use the Pyro and Shocker moves. After dispatching a wave of Druids with these moves, the Earthshaker combo is automatically unlocked for the player during the same mission.
- "Oh My Darling, Clementine" is a western folk ballad, and is likely the derivation of the Clementine's nomenclature.
- Clementine's default skin is replaced with The Love Giver skin when players either Pre-ordered the game, redeemed a promotional code, or own the PC version.
- One of Eddie's idle animations shows him grabbing Clementine, playing it while tuning it at the same time, then he lightly tosses it in the air with it spinning several times (akin to a Skateboarding kickflip), then he catches it by the neck, and places it back onto his back.